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Aluminum oxide has been proven to be neurotoxic in humans and animals. It can also be genotoxic (DNA fragmentation in the brain) in animal models and in vitro.
Cancer
A few studies have shown a possible increase in the incidence of cancer in individuals exposed to aluminium, especially in industrial workers and metallurgists. The results were not conclusive, however.
Asthma
The exposure of asthmatic patients to aluminium is very small, even compared to other metals such as iron or chromium. Moreover, respiratory symptoms often respond to conventional measures.
Dermatological toxicity
A skin irritation after repeated exposure to aluminium compounds has not been reported. Nonetheless, some products contain abrasives and aluminium oleate which may cause dermatological adverse effects.
Breast cancer
Recently, several studies have suggested that aluminium salts found in antiperspirants may be linked to the increased rates of breast cancer. These studies suggest that the aluminium in these products might be absorbed by breast cells and genetic changes occur that lead to tumours.
Toxicokinetics
The oxidation of aluminium occurs in the body and is mainly due to uptake from foodstuffs and food additives. Aluminium is mainly metabolized in the liver and excreted in urine.
Vaccinations
Various vaccines have been recommended by the World Health Organization (WHO) and the Robert Koch Institute, which have high health benefits for the individual as well as the population as a whole. Nevertheless, the additional exposure of infants and young children to aluminium via food and FCM should be as low as possible.
